The most important homeports for cruises in Florida are Miami, Port Everglades, Cape Canaveral, Tampa, and Jacksonville. Each of these ports has one or more nearby airports for travel arrangements. Consult your cruise agent for suggestions on the best airport to use based upon your travel plans.
Galveston, Texas is a good port for western Carribean cruises. Also the port of New Orleans is the home base of several cruise ships.
Alaska cruises often depart from Seattle, Vancouver, San Francisco, Sitka, Anchorage (3 areas), Juneau, Ketchikan, and Prince Rupert, BC. European homeports include Amsterdam, Athens, Barcelona, Cannes, Copenhagen, Genoa, Istanbul, Lisbon, London, Monte Carlo, Nice, Rome, Stockholm, and Venice. Any cruise line can refer you to airports that meet your travel requirements. Again, the help of a professional cruise travel agent cannot be stressed enough.